Novel Independent Trans- and Cis-Genetic Variants Associated with CYP2D6 Expression and Activity in Human Livers.

Smith, Dylan; He, Bing; Shi, Jian; Zhu, Hao-Jie; Wang, Xinwen

Smith, Dylan; He, Bing; Shi, Jian; Zhu, Hao-Jie; Wang, Xinwen.

Afiliação

Smith D; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio (D.S., X.W.); Department of Clinical Pharmacy, University of Michigan, Ann Arbor, Michigan (H.-J.Z.); Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, M
He B; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio (D.S., X.W.); Department of Clinical Pharmacy, University of Michigan, Ann Arbor, Michigan (H.-J.Z.); Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, M
Shi J; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio (D.S., X.W.); Department of Clinical Pharmacy, University of Michigan, Ann Arbor, Michigan (H.-J.Z.); Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, M
Zhu HJ; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio (D.S., X.W.); Department of Clinical Pharmacy, University of Michigan, Ann Arbor, Michigan (H.-J.Z.); Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, M
Wang X; Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio (D.S., X.W.); Department of Clinical Pharmacy, University of Michigan, Ann Arbor, Michigan (H.-J.Z.); Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, M

Drug Metab Dispos ; 52(2): 143-152, 2024 Jan 09.

Article em En | MEDLINE | ID: mdl-38050015

Assuntos

Citocromo P-450 CYP2D6; Estudo de Associação Genômica Ampla; Humanos; Citocromo P-450 CYP2D6/genética; Citocromo P-450 CYP2D6/metabolismo; Fluvoxamina; Fígado/metabolismo; Paroxetina

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP2D6 / Estudo de Associação Genômica Ampla Limite: Humans Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2024 Tipo de documento: Article País de publicação: Estados Unidos

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