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Biomedical application of terahertz imaging technology: a narrative review.
Cong, Mengyang; Li, Wen; Liu, Yang; Bi, Jing; Wang, Xiaokun; Yang, Xueqiao; Zhang, Zihan; Zhang, Xiaoxin; Zhao, Ya-Nan; Zhao, Rui; Qiu, Jianfeng.
Afiliação
  • Cong M; College of Mechanical and Electronic Engineering, Shandong Agricultural University, Tai'an, China.
  • Li W; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Liu Y; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Bi J; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Wang X; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Yang X; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhang Z; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhang X; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhao YN; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Zhao R; School of Radiology, Shandong First Medical University & Shandong Academy of Medical Sciences, Tai'an, China.
  • Qiu J; Department of Nuclear Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Quant Imaging Med Surg ; 13(12): 8768-8786, 2023 Dec 01.
Article em En | MEDLINE | ID: mdl-38106329
ABSTRACT
Background and

Objective:

Terahertz (THz) imaging has wide applications in biomedical research due to its properties, such as non-ionizing, non-invasive and distinctive spectral fingerprints. Over the past 6 years, the application of THz imaging in tumor tissue has made encouraging progress. However, due to the strong absorption of THz by water, the large size, high cost, and low sensitivity of THz devices, it is still difficult to be widely used in clinical practice. This paper provides ideas for researchers and promotes the development of THz imaging in clinical research.

Methods:

The literature search was conducted in the Web of Science and PubMed databases using the keywords "Terahertz imaging", "Breast", "Brain", "Skin" and "Cancer". A total of 94 English language articles from 1 January, 2017 to 30 December, 2022 were reviewed. Key Content and

Findings:

In this review, we briefly introduced the recent advances in THz near-field imaging, single-pixel imaging and real-time imaging, the applications of THz imaging for detecting breast, brain and skin tissues in the last 6 years were reviewed, and the advantages and existing challenges were identified. It is necessary to combine machine learning and metamaterials to develop real-time THz devices with small size, low cost and high sensitivity that can be widely used in clinical practice. More powerful THz detectors can be developed by combining graphene, designing structures and other methods to improve the sensitivity of the devices and obtain more accurate information. Establishing a THz database is one of the important methods to improve the repeatability and accuracy of imaging results.

Conclusions:

THz technology is an effective method for tumor imaging. We believe that with the joint efforts of researchers and clinicians, accurate, real-time, and safe THz imaging will be widely applied in clinical practice in the future.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Quant Imaging Med Surg Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: CHINA / CN / REPUBLIC OF CHINA

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Quant Imaging Med Surg Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China País de publicação: CHINA / CN / REPUBLIC OF CHINA