Orthostatic hypotension: Review and expert position statement.
Rev Neurol (Paris)
; 180(1-2): 53-64, 2024.
Article
em En
| MEDLINE
| ID: mdl-38123372
ABSTRACT
Orthostatic hypotension is defined as a drop in systolic blood pressure of at least 20mmHg or a drop in diastolic blood pressure of at least 10mmHg within 3minutes of standing. It is a common disorder, especially in high-risk populations such as elderly subjects and patients with neurological diseases, and is associated with markedly increased morbidity and mortality. Its management can be challenging, particularly in cases where supine hypertension is associated with severe orthostatic hypotension. Education of the patient, non-pharmacological measures, and drug adaptation are the cornerstones of treatment. Pharmacological treatment should be individualized according to the severity, underlying cause, 24-hour blood pressure profile, and associated coexisting conditions. First-line therapies are midodrine and fludrocortisone, which may need to be combined for optimal care of severe cases.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipertensão
/
Hipotensão Ortostática
/
Midodrina
/
Doenças do Sistema Nervoso
Limite:
Aged
/
Humans
Idioma:
En
Revista:
Rev Neurol (Paris)
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
França