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Reconstructive Methodology in the Synthesis of 2-Aminopurine.
Neymash, Artyom O; Ulomsky, Evgeny N; Fedotov, Victor V; Aminov, Semen V; Lyapustin, Daniil N; Gorbunov, Evgeny B; Ishimnikov, Vladislav A; Slepukhin, Pavel A; Rusinov, Vladimir L.
Afiliação
  • Neymash AO; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
  • Ulomsky EN; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
  • Fedotov VV; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
  • Aminov SV; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
  • Lyapustin DN; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
  • Gorbunov EB; Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science, Sofii Kovalevskoy St. 22, 620137 Yekaterinburg, Russia.
  • Ishimnikov VA; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
  • Slepukhin PA; Institute of Organic Synthesis, Ural Branch of the Russian Academy of Science, Sofii Kovalevskoy St. 22, 620137 Yekaterinburg, Russia.
  • Rusinov VL; Chemical Engineering Institute, Ural Federal University, 19 Mira St., 620002 Yekaterinburg, Russia.
Molecules ; 29(1)2023 Dec 25.
Article em En | MEDLINE | ID: mdl-38202717
ABSTRACT
A fundamentally new synthetic approach to the synthesis of 2-aminopurine has been developed. It consists in the combination of the creation of a condensed polyazotic heterocyclic tetrazolopyrimidine structure, its transformation into triaminopyrimidine, and its subsequent cyclization into 2-aminopurine. The structure of the obtained compounds was established based on spectral characteristics, and the structure of the intermediate compound 5 was established directly by X-ray diffraction analysis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Federação Russa País de publicação: Suíça