Parkinson's Disease Is Predominantly an Environmental Disease.
J Parkinsons Dis
; 14(3): 451-465, 2024.
Article
em En
| MEDLINE
| ID: mdl-38217613
ABSTRACT
Parkinson's disease is the world's fastest growing brain disorder, and exposure to environmental toxicants is the principal reason. In this paper, we consider alternative, but unsatisfactory, explanations for its rise, including improved diagnostic skills, aging populations, and genetic causes. We then detail three environmental toxicants that are likely among the main causes of Parkinson's disease- certain pesticides, the solvent trichloroethylene, and air pollution. All three environmental toxicants are ubiquitous, many affect mitochondrial functioning, and all can access humans via various routes, including inhalation and ingestion. We reach the hopeful conclusion that most of Parkinson's disease is thus preventable and that we can help to create a world where Parkinson's disease is increasingly rare.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Praguicidas
/
Tricloroetileno
Limite:
Humans
Idioma:
En
Revista:
J Parkinsons Dis
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Estados Unidos