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Transdermal drug delivery using a porous microneedle device driven by a hydrogel electroosmotic pump.
Wang, Gaobo; Kato, Kosuke; Aoki, Izuru; Ichinose, Sae; Inoue, Daisuke; Tottori, Soichiro; Nishizawa, Matsuhiko.
Afiliação
  • Wang G; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
  • Kato K; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
  • Aoki I; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
  • Ichinose S; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
  • Inoue D; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
  • Tottori S; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
  • Nishizawa M; Department of Finemechanics, Graduate School of Engineering, Tohoku University, 6-6-1 Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan. nishizawa@tohoku.ac.jp.
J Mater Chem B ; 12(6): 1490-1494, 2024 Feb 07.
Article em En | MEDLINE | ID: mdl-38234189
ABSTRACT
Integrating a hydrogel electroosmotic pump with a parylene C-coated porous microneedle (PMN) is developed for transdermal drug delivery applications. The hydrogel pump is fabricated by combining an anionic and a cationic hydrogel to generate enhanced electroosmosis flow (EOF) to drive the transportation of molecules via PMN.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis / Eletro-Osmose Idioma: En Revista: J Mater Chem B Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis / Eletro-Osmose Idioma: En Revista: J Mater Chem B Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão