One-Dimensional HKUST-1-Decorated Glassy Carbon Electrode for the Sensitive Electrochemical Immunosensor of NS1 Dengue Virus Serotype-3.
ACS Omega
; 9(1): 1454-1462, 2024 Jan 09.
Article
em En
| MEDLINE
| ID: mdl-38239287
ABSTRACT
In this work, simple and sensitive detection of dengue virus serotype-3 (DENV-3) antigen was accomplished by a one-dimensional (1D) HKUST-1-functionalized electrochemical sensor. 1D HKUST-1 was synthesized via a coprecipitation method using triethanolamine (TEOA) as pH modulator and structure-directing agent. The structure, morphology, and sensing performance of the HKUST-1-decorated carbon electrode were characterized by X-ray diffraction (XRD), infrared spectroscopy (FTIR), scanning electron microscopy (SEM), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). We found that 40 wt% TEOA transforms the octahedron HKUST-1 to the nanorods while maintaining its crystal structure and providing chemical stability. The 1D HKUST-1-decorated carbon electrode successfully detects the antigen in the range of 0.001-10 ng/mL with a detection limit of 0.932 pg/mL. The immunosensor also exhibits remarkable performance in analyzing the antigen in human serum and showed recovery as high as â¼98% with excellent selectivity and reproducibility.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
ACS Omega
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Indonésia