The effects of short-chain fatty acids on the neuronal membrane functions of Helix pomatia. III. 22Na efflux from the cells.
Cell Mol Neurobiol
; 6(4): 397-405, 1986 Dec.
Article
em En
| MEDLINE
| ID: mdl-3829102
ABSTRACT
The effect of short-chain fatty acids on both ouabain-sensitive and ouabain-insensitive fractions of 22Na efflux from the neurons of Helix pomatia was studied. Fatty acids, having fewer than 10 carbon atoms in the hydrocarbon chain, increased the ouabain-sensitive 22Na efflux from the neurons, while fatty acids, having more than 9 carbon atoms, inhibited the 22Na efflux in comparison with that in normal physiological solution. All the fatty acids used had an inhibiting effect on the ouabain-insensitive 22Na efflux from the cells independent on the number of carbon atoms in the hydrocarbon chain. These studies indicate that these short-chain fatty acids can be effective modulators of both ouabain-sensitive and ouabain-insensitive fractions of Na efflux from the cells.
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Base de dados:
MEDLINE
Assunto principal:
Sódio
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Ácidos Graxos
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Neurônios
Limite:
Animals
Idioma:
En
Revista:
Cell Mol Neurobiol
Ano de publicação:
1986
Tipo de documento:
Article