Prognosis of pacing-dependent patients with cardiovascular implantable electronic devices.
Herzschrittmacherther Elektrophysiol
; 35(1): 39-45, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-38294518
ABSTRACT
BACKGROUND:
Data on the prognostic significance of pacing dependency in patients with cardiovascular implantable electronic devices (CIEDs) are sparse.METHODS:
The prognostic significance of pacing dependency defined as absence of an intrinsic rhythm ≥â¯30â¯bpm was determined in 786 patients with CIEDs at the authors' institution using univariate and multivariate regression analysis to identify predictors of all-cause mortality.RESULTS:
During 49 months median follow-up, death occurred in 63 of 130 patients with pacing dependency compared to 241 of 656 patients without pacing dependency (48% versus 37%, hazard ratio [HR] 1.34; 95% confidence interval [CI] 1.02-1.78, Pâ¯= 0.04). Using multivariate regression analysis, predictors of all-cause mortality included age (HR 1.07; 95% CI 1.05-1.08, Pâ¯< 0.01), history of atrial fibrillation (HR 1.32, 95% CI 1.03-1.69, Pâ¯< 0.01), chronic kidney disease (HR 1.28; 95% CI 1.00-1.63, Pâ¯= 0.048) and New York Heart Association (NYHA) class ≥â¯III (HR 2.00; 95% CI 1.52-2.62, Pâ¯< 0.01), but not pacing dependency (HR 1.15; 95% CI 0.86-1.54, Pâ¯= 0.35).CONCLUSIONS:
In contrast to age, atrial fibrillation, chronic kidney disease and heart failure severity as indexed by NYHA functional class III or IV, pacing dependency does not appear to be an independent predictor of all-cause mortality in patients with CIEDs.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Atrial
/
Desfibriladores Implantáveis
/
Insuficiência Renal Crônica
/
Insuficiência Cardíaca
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Herzschrittmacherther Elektrophysiol
Assunto da revista:
CARDIOLOGIA
/
FISIOLOGIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Alemanha