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Advances in the pathogenesis of vulvar lichen sclerosus.
Xie, Xingkui; Wu, Kejia.
Afiliação
  • Xie X; Department of Gynecology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China.
  • Wu K; Center for Reproductive Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China. wdzn2019@163.com.
Mol Biol Rep ; 51(1): 396, 2024 Mar 07.
Article em En | MEDLINE | ID: mdl-38453810
ABSTRACT
Vulvar lichen sclerosus (VLS) is a chronic non-neoplastic skin lesion characterized by vulvar itching, pain, atrophy, whitening of the skin and mucous membranes, and gradual atrophy and disappearance of the labia minora, which can eventually lead to vulvar scarring, causing functional impairment and seriously affecting the patient's physical and mental health. VLS can occur at any age, however, its pathogenesis and etiology are not fully understood. Considerable progress has been made in related research on genetic susceptibility factors, autoimmune disorders, collagen metabolism abnormalities, and their triggering factors in disease formation and progression. This article reviews the etiology of vulvar lichen sclerosus.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Líquen Escleroso Vulvar Limite: Female / Humans Idioma: En Revista: Mol Biol Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Líquen Escleroso Vulvar Limite: Female / Humans Idioma: En Revista: Mol Biol Rep Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Holanda