BODIPY phototether enables oligonucleotide cyclization and subsequent deprotection by tissue-transparent red light.
Chem Commun (Camb)
; 60(32): 4366-4369, 2024 Apr 16.
Article
em En
| MEDLINE
| ID: mdl-38563214
ABSTRACT
meso-methyl-BODIPY photocages release a leaving group upon visible light irradiation but often lack thermal stability. In turn, our thermally-stable, red-shifted BODIPY phototether allows oligonucleotide cyclization, preventing complementary strand hybridization. Hybridization resumes upon red-NIR irradiation, disconnecting the phototether by oxidative cleavage, which is easily monitored by a blue shift in fluorescence.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
República Tcheca
País de publicação:
Reino Unido