The prospects of automation in drug discovery research using silkworms.
Drug Discov Ther
; 18(2): 130-133, 2024 Jun 06.
Article
em En
| MEDLINE
| ID: mdl-38569832
ABSTRACT
We have established several models of infectious diseases in silkworms to explore disease-causing mechanisms and identify new antimicrobial substances. These models involve injecting laboratory-cultured pathogens into silkworms and monitoring their survival over a period of days. The use of silkworms is advantageous because they are cost-effective and raise fewer ethical concerns than mammalian subjects, allowing for larger experimental group sizes. To capitalize on these benefits, there is a growing importance in mechanizing and automating the experimental processes that currently require manual labor. This paper discusses the future of laboratory automation, specifically through the mechanization and automation of silkworm-based experimental procedures.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bombyx
/
Descoberta de Drogas
/
Automação Laboratorial
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Drug Discov Ther
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Japão