Shining a light on cerebral autoregulation: Are we anywhere near the truth?

Bird, Jordan D; MacLeod, David B; Griesdale, Donald E; Sekhon, Mypinder S; Hoiland, Ryan L

Bird, Jordan D; MacLeod, David B; Griesdale, Donald E; Sekhon, Mypinder S; Hoiland, Ryan L.

Afiliação

Bird JD; Division of Critical Care Medicine, Department of Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
MacLeod DB; Collaborative Entity for REsearching BRain Ischemia (CEREBRI), University of British Columbia, Vancouver, BC, Canada.
Griesdale DE; Human Pharmacology & Physiology Lab, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Sekhon MS; Division of Critical Care Medicine, Department of Medicine, Faculty of Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
Hoiland RL; Collaborative Entity for REsearching BRain Ischemia (CEREBRI), University of British Columbia, Vancouver, BC, Canada.

J Cereb Blood Flow Metab ; 44(6): 1057-1060, 2024 Jun.

Article em En | MEDLINE | ID: mdl-38603610

ABSTRACT

ABSTRACT

The near-infrared spectroscopy (NIRS)-derived cerebral oximetry index (COx) has become popularized for non-invasive neuromonitoring of cerebrovascular function in post-cardiac arrest patients with hypoxic-ischemic brain injury (HIBI). We provide commentary on the physiologic underpinnings and assumptions of NIRS and the COx, potential confounds in the context of HIBI, and the implications for the assessment of cerebral autoregulation.

Assuntos

Circulação Cerebrovascular; Homeostase; Oximetria; Espectroscopia de Luz Próxima ao Infravermelho; Humanos; Homeostase/fisiologia; Espectroscopia de Luz Próxima ao Infravermelho/métodos; Circulação Cerebrovascular/fisiologia; Oximetria/métodos; Hipóxia-Isquemia Encefálica/fisiopatologia; Encéfalo/fisiopatologia; Encéfalo/irrigação sanguínea; Encéfalo/metabolismo; Parada Cardíaca/fisiopatologia

Palavras-chave

Near-infrared spectroscopy; cardiac arrest; cerebral autoregulation; hypoxic-ischemic brain injury; return of spontaneous circulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximetria / Circulação Cerebrovascular / Espectroscopia de Luz Próxima ao Infravermelho / Homeostase Limite: Humans Idioma: En Revista: J Cereb Blood Flow Metab Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Canadá

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