Methods, Mechanisms, and Application Prospects for Enhancing Extracellular Vesicle Uptake.
Curr Med Sci
; 44(2): 247-260, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38622425
ABSTRACT
Extracellular vesicles (EVs) are considered to be a new generation of bioinspired nanoscale drug delivery systems due to their low immunogenicity, natural functionality, and excellent biocompatibility. However, limitations such as low uptake efficiency, insufficient production, and inhomogeneous performance undermine their potential. To address these issues, numerous researchers have put forward various methods and applications for enhancing EV uptake in recent decades. In this review, we introduce various methods for the cellular uptake of EVs and summarize recent advances on the methods and mechanisms for enhancing EV uptake. In addition, we provide further understanding regarding enhancing EV uptake and put forward prospects and challenges for the development of EV-based therapy in the future.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vesículas Extracelulares
Idioma:
En
Revista:
Curr Med Sci
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China