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OmicNavigator: open-source software for the exploration, visualization, and archival of omic studies.
Ernst, Terrence R; Blischak, John D; Nordlund, Paul; Dalen, Joe; Moore, Justin; Bhamidipati, Akshay; Dwivedi, Pankaj; LoGrasso, Joe; Curado, Marco Rocha; Engelmann, Brett Warren.
Afiliação
  • Ernst TR; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Blischak JD; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Nordlund P; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Dalen J; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Moore J; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Bhamidipati A; Current Address: Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX, USA.
  • Dwivedi P; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • LoGrasso J; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Curado MR; Proteovant Therapeutics, 2500 Renaissance Blvd, King of Prussia, PA, USA.
  • Engelmann BW; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
BMC Bioinformatics ; 25(1): 162, 2024 Apr 24.
Article em En | MEDLINE | ID: mdl-38658834
ABSTRACT

BACKGROUND:

The results of high-throughput biology ('omic') experiments provide insight into biological mechanisms but can be challenging to explore, archive and share. The scale of these challenges continues to grow as omic research volume expands and multiple analytical technologies, bioinformatic pipelines, and visualization preferences have emerged. Multiple software applications exist that support omic study exploration and/or archival. However, an opportunity remains for open-source software that can archive and present the results of omic analyses with broad accommodation of study-specific analytical approaches and visualizations with useful exploration features.

RESULTS:

We present OmicNavigator, an R package for the archival, visualization and interactive exploration of omic studies. OmicNavigator enables bioinformaticians to create web applications that interactively display their custom visualizations and analysis results linked with app-derived analytical tools, graphics, and tables. Studies created with OmicNavigator can be viewed within an interactive R session or hosted on a server for shared access.

CONCLUSIONS:

OmicNavigator can be found at https//github.com/abbvie-external/OmicNavigator.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Biologia Computacional Idioma: En Revista: BMC Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Biologia Computacional Idioma: En Revista: BMC Bioinformatics Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido