Actin pushes open a leaky lumen.

Guo, Jia; Shao, Yue

Guo, Jia; Shao, Yue.

Afiliação

Guo J; Institute of Biomechanics and Medical Engineering, Applied Mechanics Laboratory, Department of Engineering Mechanics, School of Aerospace Engineering, Tsinghua University, Beijing 100084, China.
Shao Y; Institute of Biomechanics and Medical Engineering, Applied Mechanics Laboratory, Department of Engineering Mechanics, School of Aerospace Engineering, Tsinghua University, Beijing 100084, China. Electronic address: yshao@tsinghua.edu.cn.

Cell Stem Cell ; 31(5): 587-588, 2024 May 02.

Article em En | MEDLINE | ID: mdl-38701753

ABSTRACT

ABSTRACT

Using a human stem cell-based model to understand how the human epiblast forms at the very beginning of implantation, Indana et al.1 establish a role for pushing forces that are generated by apical actin polymerization and reveal a two-stage, biomechanics-driven lumen growth process underlying epiblast cavity morphogenesis.

Assuntos

Actinas; Humanos; Actinas/metabolismo; Camadas Germinativas/metabolismo; Camadas Germinativas/citologia; Morfogênese; Animais

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Actinas Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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