Ultrafast 3-D Transcutaneous Super Resolution Ultrasound Using Row-Column Array Specific Coherence-Based Beamforming and Rolling Acoustic Sub-aperture Processing: In Vitro, in Rabbit and in Human Study.
Ultrasound Med Biol
; 50(7): 1045-1057, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38702285
ABSTRACT
OBJECTIVE:
This study aimed to realise 3-D super-resolution ultrasound imaging transcutaneously with a row-column array which has far fewer independent electronic channels and a wider field of view than typical fully addressed 2-D matrix arrays. The in vivo image quality of the row-column array is generally poor, particularly when imaging non-invasively. This study aimed to develop a suite of image formation and post-processing methods to improve image quality and demonstrate the feasibility of ultrasound localisation microscopy using a row-column array, transcutaneously on a rabbit model and in a human.METHODS:
To achieve this, a processing pipeline was developed which included a new type of rolling window image reconstruction, which integrated a row-column array specific coherence-based beamforming technique with acoustic sub-aperture processing. This and other processing steps reduced the 'secondary' lobe artefacts, and noise and increased the effective frame rate, thereby enabling ultrasound localisation images to be produced.RESULTS:
Using an in vitro cross tube, it was found that the procedure reduced the percentage of 'false' locations from â¼26% to â¼15% compared to orthogonal plane wave compounding. Additionally, it was found that the noise could be reduced by â¼7 dB and the effective frame rate was increased to over 4000 fps. In vivo, ultrasound localisation microscopy was used to produce images non-invasively of a rabbit kidney and a human thyroid.CONCLUSION:
It has been demonstrated that the proposed methods using a row-column array can produce large field of view super-resolution microvascular images in vivo and in a human non-invasively.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ultrassonografia
/
Imageamento Tridimensional
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Ultrasound Med Biol
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Reino Unido