PathwayNexus: a tool for interactive metabolic data analysis.
Bioinformatics
; 40(6)2024 Jun 03.
Article
em En
| MEDLINE
| ID: mdl-38724240
ABSTRACT
MOTIVATION High-throughput omics methods increasingly result in large datasets including metabolomics data, which are often difficult to analyse. RESULTS:
To help researchers to handle and analyse those datasets by mapping and investigating metabolomics data of multiple sampling conditions (e.g. different time points or treatments) in the context of pathways, PathwayNexus has been developed, which presents the mapping results in a matrix format, allowing users to easily observe the relations between the compounds and the pathways. It also offers functionalities like ranking, sorting, clustering, pathway views, and further analytical tools. Its primary objective is to condense large sets of pathways into smaller, more relevant subsets that align with the specific interests of the user. AVAILABILITY AND IMPLEMENTATION The methodology presented here is implemented in PathwayNexus, an open-source add-on for Vanted available at www.cls.uni-konstanz.de/software/pathway-nexus. CONTACT falk.schreiber@unikonstanz.de. SUPPLEMENTARY INFORMATION Website www.cls.uni-konstanz.de/software/pathway-nexus.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Metabolômica
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Alemanha