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Controlled oxygen delivery to power tissue regeneration.
Zoneff, Elizabeth; Wang, Yi; Jackson, Colin; Smith, Oliver; Duchi, Serena; Onofrillo, Carmine; Farrugia, Brooke; Moulton, Simon E; Williams, Richard; Parish, Clare; Nisbet, David R; Caballero-Aguilar, Lilith M.
Afiliação
  • Zoneff E; The Graeme Clark Institute, The University of Melbourne, Parkville, Melbourne, VIC, Australia.
  • Wang Y; Department of Biomedical Engineering, Faculty of Engineering and Information Technology, The University of Melbourne, Parkville, Melbourne, VIC, Australia.
  • Jackson C; The Graeme Clark Institute, The University of Melbourne, Parkville, Melbourne, VIC, Australia.
  • Smith O; Department of Biomedical Engineering, Faculty of Engineering and Information Technology, The University of Melbourne, Parkville, Melbourne, VIC, Australia.
  • Duchi S; Research School of Chemistry, Australian National University, Canberra, ACT, Australia.
  • Onofrillo C; ARC Centre of Excellence in Synthetic Biology, Australian National University, Canberra, ACT, Australia.
  • Farrugia B; Research School of Chemistry, Australian National University, Canberra, ACT, Australia.
  • Moulton SE; ARC Centre of Excellence in Synthetic Biology, Australian National University, Canberra, ACT, Australia.
  • Williams R; Department of Surgery, Faculty of Medicine, Dentistry and Health Science, The University of Melbourne, Melbourne, VIC, Australia.
  • Parish C; Aikenhead Centre for Medical Discovery, St. Vincent's Hospital, Melbourne, VIC, Australia.
  • Nisbet DR; Department of Surgery, Faculty of Medicine, Dentistry and Health Science, The University of Melbourne, Melbourne, VIC, Australia.
  • Caballero-Aguilar LM; Aikenhead Centre for Medical Discovery, St. Vincent's Hospital, Melbourne, VIC, Australia.
Nat Commun ; 15(1): 4361, 2024 May 22.
Article em En | MEDLINE | ID: mdl-38778053
ABSTRACT
Oxygen plays a crucial role in human embryogenesis, homeostasis, and tissue regeneration. Emerging engineered regenerative solutions call for novel oxygen delivery systems. To become a reality, these systems must consider physiological processes, oxygen release mechanisms and the target application. In this review, we explore the biological relevance of oxygen at both a cellular and tissue level, and the importance of its controlled delivery via engineered biomaterials and devices. Recent advances and upcoming trends in the field are also discussed with a focus on tissue-engineered constructs that could meet metabolic demands to facilitate regeneration.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Regeneração / Engenharia Tecidual Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Austrália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Regeneração / Engenharia Tecidual Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Austrália