Balancing Hormone Therapy: Mitigating Adverse Effects of Androgen-Deprivation Therapy and Exploring Alternatives in Prostate Cancer Management.
Am Soc Clin Oncol Educ Book
; 44(3): e433126, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38788186
ABSTRACT
Androgen-deprivation therapy (ADT) is well established as the standard of care in metastatic prostate cancer (PCa) management; however, ADT has significant adverse effects (AEs) that must be addressed. This review aims to highlight opportunities to mitigate AEs of ADT and explore alternatives in PCa management. Specifically, we discuss behavioral and pharmacologic strategies for mitigating ADT AEs as well as ADT-sparing approaches for hormone-sensitive and castration-resistant PCa. Equipped with effective mitigation strategies and possible alternatives, clinicians and researchers can optimize health-related quality of life for patients currently receiving ADT for PCa and consider treatments that spare patients from AEs of ADT.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Qualidade de Vida
/
Antagonistas de Androgênios
Limite:
Humans
/
Male
Idioma:
En
Revista:
Am Soc Clin Oncol Educ Book
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Estados Unidos