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Sulfur fluoride exchange.
Homer, Joshua A; Xu, Long; Kayambu, Namitharan; Zheng, Qinheng; Choi, Eun Joung; Kim, Byeong Moon; Sharpless, K Barry; Zuilhof, Han; Dong, Jiajia; Moses, John E.
Afiliação
  • Homer JA; Cancer Center, Cold Spring Harbor Laboratory, 1 Bungtown Road, NY 11724, USA.
  • Xu L; Institute of Translational Medicine, Zhangjiang Institute for Advanced Study, Shanghai Jiao Tong University, Shanghai 200240, China.
  • Kayambu N; School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
  • Zheng Q; Laboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
  • Choi EJ; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Kim BM; Current affiliation: Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA.
  • Sharpless KB; Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, South Korea.
  • Zuilhof H; Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 08826, South Korea.
  • Dong J; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Moses JE; Laboratory of Organic Chemistry, Wageningen University, Stippeneng 4, 6708 WE, Wageningen, The Netherlands.
Article em En | MEDLINE | ID: mdl-38873592
ABSTRACT
Sulfur Fluoride Exchange (SuFEx) is a click reaction par excellence that has revolutionized multiple research fields. In this Primer, we delve into the essential elements of SuFEx operation, catalysis, and SuFExable connective hubs. We also explore the cutting-edge applications of SuFEx in drug development, polymer science, and biochemistry. Additionally, we examine the potential limitations and promising prospects for this versatile click reaction.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nat Rev Methods Primers Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nat Rev Methods Primers Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido