Impact of pre-existing medical conditions on mortality in geriatric trauma: a nationwide study in Japan.

ABSTRACT

PURPOSE: To investigate the relationship between pre-existing medical conditions and outcomes in elderly trauma patients in Japan. METHODS: This multicenter observational study utilized data from the Japan Trauma Data Bank (JTDB) from 2019 to 2020. The primary outcome was in-hospital mortality. Factors associated with in-hospital mortality were identified using multivariate logistic regression analysis, from which adjusted odds ratios (AOR) and 95% confidence intervals (CI) were determined. RESULTS: Of the participants during the study period, 19,598 patients were included in the analysis. Among the pre-existing medical conditions, moderate or severe liver disease showed the strongest positive association with in-hospital mortality (AOR 7.087, 95% CI 3.194-15.722), followed by multiple malignancies (AOR 3.490, 95% CI 1.046-11.641), congestive heart failure (AOR 2.572, 95% CI 1.920-3.445), and moderate or severe renal disease (AOR 2.256, 95% CI 1.584-3.215). CONCLUSION: Data from JTDB suggests that pre-existing conditions like moderate or severe liver disease, congestive heart failure, and moderate or severe renal disease in elderly trauma patients are positively correlated with in-hospital mortality.