[Research progress of CAR-macrophages in malignant hematological diseases].

Zheng, R B; Xiao, Y

Zheng, R B; Xiao, Y.

Afiliação

Zheng RB; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Xiao Y; Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

Zhonghua Xue Ye Xue Za Zhi ; 45(4): 413-416, 2024 Apr 14.

Article em Zh | MEDLINE | ID: mdl-38951075

ABSTRACT

ABSTRACT

This article reviews the development history of chimeric antigen receptor macrophage (CAR-M) therapy, discusses its application in malignant hematologic diseases, introduces related clinical trials, analyzes the advantages and challenges faced by CAR-M therapy in clinical application, and looks forward to its future use in the treatment of malignant hematologic diseases.

Assuntos

Neoplasias Hematológicas; Macrófagos; Humanos; Neoplasias Hematológicas/terapia; Macrófagos/imunologia; Receptores de Antígenos Quiméricos/imunologia; Imunoterapia Adotiva/métodos; Doenças Hematológicas/terapia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Hematológicas / Macrófagos Limite: Humans Idioma: Zh Revista: Zhonghua Xue Ye Xue Za Zhi Ano de publicação: 2024 Tipo de documento: Article País de afiliação: China País de publicação: China

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