Pd-Catalyzed Aerobic Synthesis of Allylic Sulfones from Allylic Alcohols and Sulfonyl Hydrazines in Water.
J Org Chem
; 89(14): 10344-10348, 2024 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-38984991
ABSTRACT
A mild and green synthesis of allylic sulfones from allylic alcohols and sulfonyl hydrazines was developed in water media. The simple and commercially available Pd(PPh3)4 is used as the best catalyst, and the reaction can proceed smoothly at 40 °C under air. This new method does not require the common nitrogen protection and organic media, and can be readily scaled up in gram scale, showing the good practicality value.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Org Chem
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China