A single bout of jumping exercise does not modulate serum markers of bone formation or bone resorption throughout a 24â¯h period.
Bone
; : 117216, 2024 Jul 27.
Article
em En
| MEDLINE
| ID: mdl-39074570
ABSTRACT
INTRODUCTION:
This randomized, cross-over trial assessed the effect of a single bout of high-impact exercise on serum markers of bone formation and bone resorption over a 24â¯h period.METHODS:
Twenty healthy males and females performed a single bout of brief jumping exercise (EXC) or no exercise (CON), 55â¯min following consumption of a standard breakfast. Blood markers of bone formation (P1NP) and bone resorption (CTXI) were assessed before (tâ¯=â¯0â¯h) and over a 5â¯h period after breakfast, and following 24â¯h of post-exercise recovery (tâ¯=â¯24â¯h).RESULTS:
Serum CTX-I concentrations decreased during the 5â¯h postprandial period (time-effect, Pâ¯<â¯0.001) with no differences between conditions (time x condition, Pâ¯=â¯0.14). After aâ¯~â¯16â¯% decline during the first 30â¯min following breakfast, serum P1NP concentrations gradually returned to baseline values during the 5â¯h postprandial period, with no differences in the overall response between conditions (time-effect, Pâ¯<â¯0.001; time x condition, Pâ¯=â¯0.25). Fasted serum CTX-I concentrations decreased from 0.33⯱â¯0.15 and 0.35⯱â¯0.15â¯ng/mL at baseline, to 0.31⯱â¯0.13 and 0.31⯱â¯0.16â¯ng/mL at tâ¯=â¯24â¯h in CON and EXC, respectively, with no differences between conditions (time-effect, Pâ¯<â¯0.01; time x condition, Pâ¯=â¯0.70). Fasted serum P1NP concentrations did not change from baseline to tâ¯=â¯24â¯h in both CON (baseline 76⯱â¯27â¯ng/mL, tâ¯=â¯24â¯h 79⯱â¯26â¯ng/mL) and EXC (baseline 80⯱â¯24â¯ng/mL, tâ¯=â¯24â¯h 77⯱â¯29â¯ng/mL; time-effect, Pâ¯=â¯0.89), with no differences between conditions (time x condition, Pâ¯=â¯0.22).CONCLUSION:
High-impact exercise does not modulate the concentrations of the serum marker of bone formation P1NP and the serum marker of bone resorption CTX-I throughout a 24â¯h recovery period in healthy adults.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Bone
Assunto da revista:
METABOLISMO
/
ORTOPEDIA
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Holanda