Cruciferous vegetables intake reduces pancreatic cancer risk: an updated systematic review with meta-analysis.
Eur J Nutr
; 2024 Jul 30.
Article
em En
| MEDLINE
| ID: mdl-39078523
ABSTRACT
PURPOSE:
The escalating disease burden associated with pancreatic cancer has led to its inclusion as a target of public health efforts. The relationship between the consumption of cruciferous vegetables and the incidence of pancreatic cancer has generated conflicting findings in various epidemiological studies.METHODS:
Eligible studies were cohort or case-control studies reporting on the association between consumption of cruciferous vegetables and pancreatic cancer. PubMed, Cochrane, and Embase were systematically searched for potential studies before 27 July2022. These databases were finally searched again on 1 February 2023. The meta-analysis was conducted using random-effects models, and Stata 17 was employed for the statistical analyses.RESULTS:
Sixteen studies, encompassing 1,135,281 participants from 1989 to 2021, met the inclusion criteria. An inverse association of statistical significance was observed (RR 0.83, 95% CI 0.72-0.96). The sensitivity analysis indicates that this result is robust. We conducted subgroup analyses based on region, gender, study design, quality, exclusivity to endocrine tumors, adjustment for smoking, alcohol consumption, diabetes, and BMI.CONCLUSION:
This review provided support for the inclusion of cruciferous vegetables in the diet as a cost-effective and readily available prevention.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Eur J Nutr
Assunto da revista:
CIENCIAS DA NUTRICAO
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
China