An evidence based comprehensive review on thiacloprid, a pesticide residue, induced toxicity: Unveiling hazard to human health.
Environ Toxicol Pharmacol
; 110: 104532, 2024 Sep.
Article
em En
| MEDLINE
| ID: mdl-39134163
ABSTRACT
Thiacloprid, a hazardous neonicotinoid insecticide, prevalent in daily agricultural practices, raises concerns due to the harmful effects of its residues on food items, and on unintended organisms poses a significant threat to human health. Introduced in 1990, Thiacloprid have gained popularity for its perceived effectiveness and reduced risks to non-target animals. However, emerging research in recent years reports significant toxic effects of Thiacloprid on non-target species, spanning neurotoxicity, immunotoxicity, hepatotoxicity, nephrotoxicity, and reproductive issues. Mammalian studies, particularly involving rodents, reveal cognitive impairment, hippocampal damage, and hepatic abnormalities upon Thiacloprid exposure. Reproductive toxicity and DNA damage are imminent concerns, disrupting gestational epigenetic reprogramming and suggesting persistent effects on future generations. Genotoxic effects, Embryotoxic, and observed reproductive toxicity accentuate the need for caution in the utilization of Thiacloprid. This review highlights reported toxic effects produced by Thiacloprid in recent years, challenging the initial belief in its lower toxicity for vertebrates.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tiazinas
/
Resíduos de Praguicidas
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Neonicotinoides
/
Inseticidas
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Environ Toxicol Pharmacol
Ano de publicação:
2024
Tipo de documento:
Article
País de publicação:
Holanda