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The predictive role of the total potassium intake and odds of breast cancer: a case-control study.
Ahmadirad, Hamid; Norouzzadeh, Mostafa; Teymoori, Farshad; Jahromi, Mitra Kazemi; Farhadnejad, Hossein; Babrpanjeh, Mitra; Mokhtari, Ebrahim; Heidari, Zeinab; Mirmiran, Parvin; Rashidkhani, Bahram.
Afiliação
  • Ahmadirad H; Student Research Committee, Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Norouzzadeh M; Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Teymoori F; Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Jahromi MK; Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
  • Farhadnejad H; Nutritional Sciences Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Babrpanjeh M; Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
  • Mokhtari E; Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, BandarAbbas, Iran.
  • Heidari Z; Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mirmiran P; Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Rashidkhani B; Nutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMC Cancer ; 24(1): 995, 2024 Aug 12.
Article em En | MEDLINE | ID: mdl-39134992
ABSTRACT
BACKGROUNDS Dietary potassium can play an important role in decreasing inflammatory factors as a protective factor for cancers. In this case-control study, we aimed to assess the possible association between dietary potassium intake and the risk of breast cancer (BC) among Iranian adult women.

METHODS:

The present case-control study was conducted at Shohada and Imam Hossain hospitals, in Tehran. The study included 134 newly diagnosed cases of BC and 267 controls. A validated semi-quantitative 168-item food frequency questionnaire was used to compute the potassium intake. Logistic regression, adjusted for potential confounders, was used to estimate odds ratios(ORs) and 95% confidence intervals(CI) of BC according to tertiles of potassium intake.

RESULTS:

The mean(M) ± standard deviation(SD) of age and body mass index (BMI) were 47.9 ± 10.3 years and 29.4 ± 5.5 kg/m2, respectively. Also, the M ± SD of potassium intake for the control and case groups was 1616 ± 293 and 1542 ± 338 (mg/1000 Kcal), respectively. In the multivariable-adjusted model for potential confounders, the higher total potassium intake was associated with decreased odds of BC (OR 0.35, 95%CI 0.19-0.62, P for trend < 0.001). Moreover, an inverse relationship was observed between potassium from plant sources (OR 0.39, 95%CI 0.22-0.69, P for trend = 0.001) and fruit and vegetable sources (OR 0.49, 95%CI 0.28-0.87, P for trend = 0.016) and odds of BC.

CONCLUSIONS:

Our findings suggested that diet rich in potassium may have a predictive role to reduce the odds of BC.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Limite: Adult / Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Irã País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Limite: Adult / Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Irã País de publicação: Reino Unido