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Empowering the biomedical research community: Innovative SAS deployment on the All of Us Researcher Workbench.
Humes, Izabelle; Shyr, Cathy; Dillon, Moira; Liu, Zhongjie; Peterson, Jennifer; Jeor, Chris St; Malkes, Jacqueline; Master, Hiral; Mapes, Brandy; Azuine, Romuladus; Mack, Nakia; Abdelbary, Bassent; Gamble-George, Joyonna; Goldmann, Emily; Cook, Stephanie; Choupani, Fatemeh; Baskir, Rubin; McMaster, Sydney; Lunt, Chris; Watson, Karriem; Lee, Minnkyong; Schwartz, Sophie; Munshi, Ruchi; Glazer, David; Banks, Eric; Philippakis, Anthony; Basford, Melissa; Roden, Dan; Harris, Paul A.
Afiliação
  • Humes I; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
  • Shyr C; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
  • Dillon M; Verily Life Sciences, San Francisco, CA 94080, United States.
  • Liu Z; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, United States.
  • Peterson J; SAS Institute, Cary, NC 27513, United States.
  • Jeor CS; Zencos, Cary, NC 27518, United States.
  • Malkes J; SAS Institute, Cary, NC 27513, United States.
  • Master H; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
  • Mapes B; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
  • Azuine R; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • Mack N; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • Abdelbary B; College of Health Professions, The University of Texas Rio Grande Valley, Edinburg, TX 78539, United States.
  • Gamble-George J; School of Public Health, Yale University, New Haven, CT 06510, United States.
  • Goldmann E; School of Global Public Health, New York University, New York, NY 10003, United States.
  • Cook S; School of Global Public Health, New York University, New York, NY 10003, United States.
  • Choupani F; College of Nursing, Seattle University, Seattle, WA 98122, United States.
  • Baskir R; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • McMaster S; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • Lunt C; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • Watson K; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • Lee M; All of Us Research Program Office, National Institutes of Health, Bethesda, MD 20892, United States.
  • Schwartz S; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, United States.
  • Munshi R; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, United States.
  • Glazer D; Verily Life Sciences, San Francisco, CA 94080, United States.
  • Banks E; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, United States.
  • Philippakis A; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, United States.
  • Basford M; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
  • Roden D; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
  • Harris PA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN 37203, United States.
Article em En | MEDLINE | ID: mdl-39135439
ABSTRACT

OBJECTIVES:

The All of Us Research Program is a precision medicine initiative aimed at establishing a vast, diverse biomedical database accessible through a cloud-based data analysis platform, the Researcher Workbench (RW). Our goal was to empower the research community by co-designing the implementation of SAS in the RW alongside researchers to enable broader use of All of Us data. MATERIALS AND

METHODS:

Researchers from various fields and with different SAS experience levels participated in co-designing the SAS implementation through user experience interviews.

RESULTS:

Feedback and lessons learned from user testing informed the final design of the SAS application.

DISCUSSION:

The co-design approach is critical for reducing technical barriers, broadening All of Us data use, and enhancing the user experience for data analysis on the RW.

CONCLUSION:

Our co-design approach successfully tailored the implementation of the SAS application to researchers' needs. This approach may inform future software implementations on the RW.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Am Med Inform Assoc Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Am Med Inform Assoc Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido