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A case report of dipeptidyl peptidase 4 inhibitor-related kidney disease combined with renal cancer.
Kurihara, Shigekazu; Sawa, Naoki; Sumida, Keiichi; Ikuma, Daisuke; Oba, Yuki; Mizuno, Hiroki; Sekine, Akinari; Yamanouchi, Masayuki; Hasegawa, Eiko; Suwabe, Tatsuya; Urakami, Shinji; Kono, Kei; Kinowaki, Keiichi; Ohashi, Kenichi; Yamaguchi, Yutaka; Ubara, Yoshifumi.
Afiliação
  • Kurihara S; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Sawa N; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Sumida K; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Ikuma D; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Oba Y; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Mizuno H; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Sekine A; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Yamanouchi M; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Hasegawa E; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Suwabe T; Nephrology Center and the Okinaka Memorial Institute for Medical Research, Toranomon Hospital, Tokyo, Japan.
  • Urakami S; Department of Urology, Toranomon Hospital, Tokyo, Japan.
  • Kono K; Department of Pathology, Toranomon Hospital, Tokyo, Japan.
  • Kinowaki K; Department of Pathology, Toranomon Hospital, Tokyo, Japan.
  • Ohashi K; Department of Pathology, Toranomon Hospital, Tokyo, Japan.
  • Yamaguchi Y; Department of Human Pathology, Tokyo Medical Dental University, Tokyo, Japan.
  • Ubara Y; Yamaguchi's Pathology Laboratory, Chiba, Japan.
Front Nephrol ; 4: 1409098, 2024.
Article em En | MEDLINE | ID: mdl-39135967
ABSTRACT
A kidney biopsy was performed in a 64-year-old woman with type 2 diabetes mellitus and less than 1 g of proteinuria who rapidly progressed to end-stage renal failure after approximately 2 years of treatment with two dipeptidyl peptidase 4 (DPP-4) inhibitors for type 2 diabetes mellitus. The biopsy revealed not only a coincidental diagnosis of renal cell carcinoma, which was not evident on pre-biopsy computed tomography, but also severe thrombotic microangiopathy (TMA)-like glomerular endothelial cell damage in the noncancerous areas. These results suggest that DPP4 inhibitors may have been involved in two kidney diseases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Nephrol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão País de publicação: CH / SUIZA / SUÍÇA / SWITZERLAND
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Nephrol Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Japão País de publicação: CH / SUIZA / SUÍÇA / SWITZERLAND