Obesity-associated Inflammation and Alloimmunity.
Transplantation
; 2024 Aug 28.
Article
em En
| MEDLINE
| ID: mdl-39192462
ABSTRACT
Obesity is a worldwide health problem with a rapidly rising incidence. In organ transplantation, increasing numbers of patients with obesity accumulate on waiting lists and undergo surgery. Obesity is in general conceptualized as a chronic inflammatory disease, potentially impacting alloimmune response and graft function. Here, we summarize our current understanding of cellular and molecular mechanisms that control obesity-associated adipose tissue inflammation and provide insights into mechanisms affecting transplant outcomes, emphasizing on the beneficial effects of weight loss on alloimmune responses.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Transplantation
Ano de publicação:
2024
Tipo de documento:
Article
País de afiliação:
Marrocos