Amine-bearing hydrocarbon cross-links: Tailoring helix stability, hydrophilicity, and synthetic adaptability in peptides.

Tran, Duc V H; Pham, Thanh K; Kim, Young-Woo

Tran, Duc V H; Pham, Thanh K; Kim, Young-Woo.

Afiliação

Tran DVH; College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea; Intergrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Pham TK; College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea; Intergrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Kim YW; College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea; Intergrated Research Institute for Drug Development, College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea. Electronic address: ywkim730@dongguk.edu.

Bioorg Med Chem ; 112: 117893, 2024 Aug 22.

Article em En | MEDLINE | ID: mdl-39197182

Palavras-chave

Amine cross-link; Peptide drugs; Peptide stapling; Ring-closing metathesis; α-Helix

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2024 Tipo de documento: Article País de publicação: Reino Unido

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