Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice.
J Exp Med
; 162(1): 358-62, 1985 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-3925068
ABSTRACT
Administration of the monoclonal antibody M7/20, which binds to the murine interleukin-2 (IL) receptor, significantly prolongs cardiac allograft survival in two H-2-incompatible strain combinations of inbred mice. The results support the important role of the IL-2 receptor in the mechanism of graft rejection, and suggest its suitability as a target for immunosuppressive therapy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores Imunológicos
/
Transplante de Coração
/
Sobrevivência de Enxerto
/
Anticorpos Monoclonais
Limite:
Animals
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1985
Tipo de documento:
Article