[Embryonal malformation following etretinate therapy of Darier's disease in the mother]. / Embryonale Fehlbildung bei Etretinat-Therapie der Mutter wegen Morbus Darier.
Dtsch Med Wochenschr
; 111(2): 60-2, 1986 Jan 10.
Article
em De
| MEDLINE
| ID: mdl-3940838
ABSTRACT
A 22-year-old woman suffering from dyskeratosis follicularis Darier became pregnant 4 months after the last dose of etretinate (Tigason). The pregnancy was terminated in the 10th week because of teratogenic risk. The pathological examination of the fetus revealed severe malformation of the left leg with aplasia of tibia and fibula, as well as hypoplasia of the left femur. This observation emphasises the necessity of effective contraception even after discontinuation of etretinate therapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Complicações na Gravidez
/
Anormalidades Induzidas por Medicamentos
/
Anormalidades Múltiplas
/
Etretinato
/
Doença de Darier
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
De
Revista:
Dtsch Med Wochenschr
Ano de publicação:
1986
Tipo de documento:
Article