[The connective tissue component and its connections with the terminal circulatory unit in macrophlebopathies]. / La composante conjonctive et ses connexions avec l'unité circulatoire terminale dans les macrophlébopathies.

We forget too often that the primitive mesenchyme cells are at the origin of healthy microvessels, lymphatic canaliculi and the conjunctival interstitium. In our different disciplines we tend to study in isolation the terminal circulatory unit, the lymphatic system, and the conjunctival tissues. Why not refer from the outset to histangiopathy in clinical situations as common as varicose illness, certain post-thrombotic syndromes and, in its classic form, to histangiopathy of stasis? In varicose illness, the conjunctival component of the vein wall is quantitatively differentiated from the normal wall; it is responsible for histochemical anomalies, and the inhomogeneities encountered are determined by the variable conditions of mechanomorphosis. There are also those very specific immunological reactions which some people have made so bold as to deny and changes in the ultrastructure, especially lysosomal changes which are not necessarily irreversible. Since 1965, amongst the post-thrombotic syndromes, Mario Degni has, with the aid of anatomopathological sections, isolated a very specific situation following parietal inflammatory lesions not the affection of the wall and valvules; the treatment of this is especially singular because the conjunctiva play a major part here and "parietal lymphostasis" is absent. There are many microvasculoconjunctival connections in the histo-angiopathy of stasis which are to be met in macrophlebopathies; they are responsible for the various clinical, capillaroscopic and histological pictures. The part played by the derivative channels, the tissular canals and the lymphatic canaliculi is important. The part played by the conjunctiva is even more important because of its retroactive information regulation. In pathological cases it is a degradation of plastic polymers.