Effects of S-methylmethionine (vitamin U) on experimental nephrotic hyperlipidemia.
Arzneimittelforschung
; 29(10): 1517-20, 1979.
Article
em En
| MEDLINE
| ID: mdl-583214
ABSTRACT
The effects of S-methylmethionine sulfonium chloride (MMSC, vitamin U) on aminonucleoside-induced nephrotic hyperlipidemia in rats were investigated. We found that repeated oral administration of MMSC (dose daily 1000 mg/kg) exhibited significant amelioration of plasma chloresterol and phospholipids levels. Also, the treatment improved nephrotic syndrome itself by producing an increase of urinary volume and a decrease of urinary protein excretion. The results suggest that MMSC may be useful as single or combined therapy for human nephrotic syndrome and its related hyperlipidemia as a safety drug.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vitamina U
/
Vitaminas
/
Hiperlipidemias
/
Nefrose
Limite:
Animals
Idioma:
En
Revista:
Arzneimittelforschung
Ano de publicação:
1979
Tipo de documento:
Article