Antibody response of immunodeficient (xid) CBA/N mice to Escherichia coli 0113 lipopolysaccharide, a thymus-independent antigen.
J Exp Med
; 157(4): 1197-207, 1983 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-6187886
ABSTRACT
CBA/N mice, which possess an X-linked immunodeficiency (xid), produce a convincing antibody response to lipopolysaccharide derived from Escherichia coli 0113 (LPS 0113), a thymus-independent antigen. The antibody response produced was shown to be specific for the O-polysaccharide moiety of LPS 0113, rather than lipid A or lipid-A-associated protein. The relevance of this finding to the nature of the genetic defect of xid-mice is discussed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lipopolissacarídeos
/
Camundongos Endogâmicos CBA
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Anticorpos Antibacterianos
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Antígenos T-Independentes
Limite:
Animals
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1983
Tipo de documento:
Article