[Cytochemical study of granulocyte enzymes in germ-free animals with adenovirus infections]. / Tsitokhimicheskoe izuchenie fermentov granulotsitov u gnotobiotikov pri adenovirusnoi infektsii.
Vopr Virusol
; (2): 231-4, 1981.
Article
em Ru
| MEDLINE
| ID: mdl-6267824
ABSTRACT
The activity of some dehydrogenases and hydrolases was studied by cytochemical methods in the peripheral blood neutrophils of germ-free guinea pigs infected with adenoviruses. The gnotobiotic animals were obtained by hysterotomy in an operation isolation room after which they were transferred into manipulation isolation room and infected with human adenovirus type 1. A depression of enzymes of alpha-glycerophosphate shunt and NADP-H2-diaphorase in neutrophils two days after infection and activation of lactate dehydrogenase and acid phosphatase at 4 days were demonstrated. The pattern of changes in the enzymatic status of intact and infected gnotobiotic animals allowed a diagnosis of adenovirus infection in most cases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Adenoviridae
/
Ensaios Enzimáticos Clínicos
/
Vida Livre de Germes
/
Neutrófilos
Limite:
Animals
Idioma:
Ru
Revista:
Vopr Virusol
Ano de publicação:
1981
Tipo de documento:
Article