[Insulin, peptide C and glucide tolerance in chronic alcoholic hepatopathies]. / Insulina, peptide C e tolleranza glucidica nelle epatopatie alcoliche croniche.
Minerva Med
; 75(34): 1933-8, 1984 Sep 08.
Article
em It
| MEDLINE
| ID: mdl-6384824
ABSTRACT
Changes in blood glucose and insulin metabolism, both under basal conditions and after glucose and glucagon stimulus, were studied in 95 patients with chronic alcoholic hepatopathy. Peptide C was also determined in 19 patients. A high incidence of islet-cell insufficiency was noted. Stress is laid on the multiplicity of the pathogenetic mechanisms responsible for blood glucose and insulin changes during chronic alcoholic hepatopathy, particularly liver cell damage, hyperglucagonaemia, organic and/or functional islet-cell insufficiency, and peripheral insulin resistance. It is felt that the last two of these are of major importance, whereas liver cell damage is of secondary significance, at any rate as far as glucose and insulin turnover is concerned.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeo C
/
Insulina
/
Hepatopatias Alcoólicas
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
It
Revista:
Minerva Med
Ano de publicação:
1984
Tipo de documento:
Article