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Effect of streptozotocin diabetes on sialic acid content and glycoprotein binding of isolated hepatocytes.
Horm Metab Res ; 12(6): 247-51, 1980.
Article em En | MEDLINE | ID: mdl-6447658
The possible correlation between sialic acid content of hepatocyte plasma membranes, and their binding capacity was investigated. For that purpose, [3H] asialotransferrin binding was tested with hepatocytes from both normal and streptozotocin treated rats. The observed decrease in binding capacity was parallel to a decrease in the sialic acid content Insulin therapy restored simultaneously normal blood glucose level, hepatic membrane sialic acid content and binding capacity.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Assialoglicoproteínas / Ácidos Siálicos / Transferrina / Diabetes Mellitus Experimental Limite: Animals Idioma: En Revista: Horm Metab Res Ano de publicação: 1980 Tipo de documento: Article País de publicação: Alemanha
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Assialoglicoproteínas / Ácidos Siálicos / Transferrina / Diabetes Mellitus Experimental Limite: Animals Idioma: En Revista: Horm Metab Res Ano de publicação: 1980 Tipo de documento: Article País de publicação: Alemanha