A novel process for the production of penitrem mycotoxins by submerged fermentation of Penicillium nigricans.
J Gen Microbiol
; 130(5): 1293-8, 1984 May.
Article
em En
| MEDLINE
| ID: mdl-6470667
ABSTRACT
A strain of Penicillium nigricans, which produces both the antifungal antibiotic griseofulvin and tremorgenic penitrem mycotoxins concurrently in static liquid culture, also elaborated both metabolites in submerged culture when stimulated by calcium chloride to sporulate. Maximum yield of penitrems (60 mg l-1) occurred within 5 d in a 60 l stirred fermenter, thus constituting the first significant process for penitrem production in submerged culture.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Penicillium
/
Fermentação
/
Micotoxinas
Idioma:
En
Revista:
J Gen Microbiol
Ano de publicação:
1984
Tipo de documento:
Article
País de publicação:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM