Sister-chromatid exchange frequency in lymphocytes of smoking and nonsmoking mothers and their newborn infants.
Mutat Res
; 121(3-4): 241-6, 1983 Sep.
Article
em En
| MEDLINE
| ID: mdl-6621586
ABSTRACT
Sister-chromatid exchange (SCE) frequency in lymphocytes of 8 smoking mothers and their 9 newborns (one subject bearing twins) was compared to 6 mothers who had never smoked and their 6 newborn infants. Mothers in the first group were required to have smoked throughout pregnancy and to have a minimum of 15 pack-years smoking history. Results confirm our earlier smoking effect reported for adults, deny an effect on the newborn, and concur with other studies that show neonates have consistently lower SCE frequencies than adults. Overall, results are consistent with the idea that toxic substances in tobacco smoke interact with chromosomal DNA of circulating human lymphocytes.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Troca de Cromátide Irmã
/
Recém-Nascido
/
Linfócitos
/
Fumar
/
Troca Genética
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Mutat Res
Ano de publicação:
1983
Tipo de documento:
Article