Increased activation effects of succinylcholine in neurological patients.
Ital J Neurol Sci
; 4(1): 27-33, 1983 Apr.
Article
em En
| MEDLINE
| ID: mdl-6862844
ABSTRACT
Succinylcholine, a depolarizing muscle relaxant with both activating and desensitizing effects, is used to facilitate endotracheal intubation. The activating effects were found to be above-normal on induction of anesthesia in 7 neurological patients generalized muscle spasm in 1 myotonic patient, contractures or prolonged contractions in "anatomically" denervated muscles (1 patient), in "functionally" denervated muscles (1 patient) and in "centrally" denervated muscles (4 patients). One of these four presented hyperkalemia and cardiocirculatory collapse. It is important to differentiate these anomalous responses to succinylcholine from those occurring as early signs of rhabdomyolysis or malignant hyperthermia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Succinilcolina
/
Procedimentos Neurocirúrgicos
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ital J Neurol Sci
Ano de publicação:
1983
Tipo de documento:
Article