A cytotoxic diacetylene from Dendropanax arboreus.
Planta Med
; 61(5): 470-1, 1995 Oct.
Article
em En
| MEDLINE
| ID: mdl-7480210
ABSTRACT
The crude ethanol extract from the leaves of Dendropanax arboreus (Araliaceae) from Monteverde, Costa Rica, exhibits cytotoxic activity against Hep-G2, A-431, H-4IIE, and L-1210 tumor cell lines, but is not toxic against normal hepatocytes. The active component has been isolated by activity-directed separation and identified by 1H- and 13C-NMR spectroscopy as the acetylenic compound cis-1,9,16-heptadecatriene-4,6-diyne-3,8-diol.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Alcinos
/
Álcoois Graxos
/
Panax
/
Antineoplásicos Fitogênicos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Planta Med
Ano de publicação:
1995
Tipo de documento:
Article