Experimental osteonecrosis of the lunate. Revascularization may cause collapse.
J Hand Surg Br
; 19(5): 565-9, 1994 Oct.
Article
em En
| MEDLINE
| ID: mdl-7529814
ABSTRACT
Is lunate collapse in Kienböck's disease a consequence of spontaneous revascularization, leading to focal osteolysis? A literature review of osteonecrosis in other locations such as the femoral head and bone allografts showed clearly that the loss of mechanical integrity is due to cellular processes which follow the spontaneous restoration of blood supply. We found no evidence in the literature that the lunate has been shown to be avascular at the time of collapse. On the contrary, increased osteoclastic activity has been reported. We excised and reimplanted the lunate in two monkeys, and found spontaneous revascularization, leading to increased osteoblastic activity. Other parts of the bone were destroyed by osteoclasts, leading to collapse. This histological example suggests that it may be possible to make an analogy with osteonecrosis in other locations. Thus, changes on plain radiography may indicate that the bone is revascularized spontaneously. Before performing operative revascularization of the lunate, one should consider that revascularization is a probable cause for collapse.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteocondrite
/
Osteonecrose
/
Ossos do Carpo
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
J Hand Surg Br
Ano de publicação:
1994
Tipo de documento:
Article
País de afiliação:
Suécia