Amphetamine-induced conditioned activity in rats: comparison with novelty-induced activity and role of the basolateral amygdala.
Behav Neurosci
; 109(4): 723-33, 1995 Aug.
Article
em En
| MEDLINE
| ID: mdl-7576216
ABSTRACT
A within-subject design was used to investigate the behavioral and neural basis of the conditioned activity induced by amphetamine in male Wistar rats. In this design, conditioned activity was inferred when the activity of a given rat following a vehicle injection was greater in its amphetamine-paired environment (CS+) than in its vehicle-paired environment (CS-). Conditioned activity (a) did not change in magnitude with the number of conditioning sessions, (b) did not differ from the level of activity recorded during the first exposure to the CS- (novelty), (c) had an extinction rate that was similar to the rate of habituation to the CS-, and (d) was not impaired by a bilateral excitotoxic lesion of the basolateral amygdala. Results are discussed in light of the incentive conditioning and habituation theories of conditioned activity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nível de Alerta
/
Condicionamento Clássico
/
Dextroanfetamina
/
Atividade Motora
Limite:
Animals
Idioma:
En
Revista:
Behav Neurosci
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
França