Valproate in the treatment of behavioral agitation in elderly patients with dementia.
J Neuropsychiatry Clin Neurosci
; 7(3): 314-9, 1995.
Article
em En
| MEDLINE
| ID: mdl-7580190
ABSTRACT
Ten nursing home patients ages 71 to 94 years with dementia and behavioral agitation were treated prospectively with open-label valproate at doses of 375 to 750 mg/day over periods of time ranging from 4 to 34 weeks. Change in behavioral agitation was rated by nursing staff members. Eight (80%) of the 10 patients showed a 50% or greater reduction in the frequency of episodes of behavioral agitation. Response was maintained in all patients. Side effects were minimal. The authors conclude that valproate may be an effective, well tolerated, and safe treatment for behavioral agitation in elderly patients with dementia.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Agitação Psicomotora
/
Antipsicóticos
/
Ácido Valproico
/
Demência
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Neuropsychiatry Clin Neurosci
Assunto da revista:
NEUROLOGIA
/
PSIQUIATRIA
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Estados Unidos
País de publicação:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA