Relaxometry of noncalcified human meningiomas. Correlation with histology and solids content.
Invest Radiol
; 30(1): 49-55, 1995 Jan.
Article
em En
| MEDLINE
| ID: mdl-7759217
ABSTRACT
RATIONALE AND OBJECTIVES:
Resected meningiomas were examined by relaxometry and light microscopy to evaluate the potential of magnetic resonance imaging (MRI) for identifying histologic subtypes and for discriminating among benign, radiation therapy-induced, and malignant meningiomas.METHODS:
The magnetic field dependence of 1/T1 of water protons (nuclear magnetic relaxation dispersion [NMRD] profile) and the water content (dry weight) were measured for 67 specimens, and the data were compared with histology. Only noncalcified, nonhemorrhagic meningiomas are reported.RESULTS:
No correlations were found between NMRD profiles, dry weight, and any histologic subtype, in contrast to an analogous study of astrocytomas. Rather, meningiomas have a broader variability of dry weight and 1/T1 than related parenchyma but a much narrower range than all grades of astrocytomas. The mean value of 1/T1, at all fields, is slightly higher in meningiomas--and the mean water content about the same--as adult cortical gray matter.CONCLUSION:
Meningiomas are frequently isointense with cortex, and histologic subtypes cannot be differentiated at any magnetic field strength by MRI using only T1- or proton density-weighted MRI.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Meníngeas
/
Meningioma
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Invest Radiol
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Estados Unidos