Cloning and initial characterization of the Bordetella pertussis fur gene.
Curr Microbiol
; 30(4): 223-6, 1995 Apr.
Article
em En
| MEDLINE
| ID: mdl-7765895
ABSTRACT
In several Gram-negative pathogens the fur (ferric uptake regulator) gene product controls the expression of many genes involved in iron uptake and virulence. To facilitate the study of iron-regulated gene expression in Bordetella pertussis, we cloned the fur gene from this organism. The B. pertussis fur gene product was 54% identical to the Escherichia coli Fur and complemented two E. coli fur mutants. As with the E. coli fur gene, sequences upstream of the B. pertussis fur were homologous to the consensus Fur-binding site and to the consensus catabolite activator protein binding site.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bordetella pertussis
/
Genes Reguladores
/
Genes Bacterianos
/
Ferro
Idioma:
En
Revista:
Curr Microbiol
Ano de publicação:
1995
Tipo de documento:
Article