[Right ventricular thrombi in primary antiphospholipid syndrome]. / Rechtsventrikuläre Thromben bei primärem Antiphospholipid-Syndrom.
Dtsch Med Wochenschr
; 120(19): 676-80, 1995 May 12.
Article
em De
| MEDLINE
| ID: mdl-7768162
ABSTRACT
Over a period of several months a 33-year-old man had recurrent pulmonary emboli. No thromboses could be demonstrated in the peripheral venous system. Transoesophageal echocardiography showed two spherical space-occupying structures in the right ventricle which were removed operatively under the suspected diagnosis of multilobular myxomas. However, their histological examination revealed pure thrombi that had grown by apposition. This unusual findings of right-ventricular thrombi could not be explained pre- and intraoperatively by any local thrombi-favouring changes in the right heart. Tests of clotting mechanisms demonstrated lupus anticoagulant (kaolin-clotting-time mixture test LA index 21.7 [normal < 15]), as well as an increased IgG cardiolipin antibody concentration of 19.3 U/l). As no underlying disease was discovered, the diagnosis was by definition primary antiphospholipid syndrome. No further thrombo-embolism has occurred during continuing oral anticoagulation with phenprocoumon.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trombose
/
Síndrome Antifosfolipídica
/
Cardiopatias
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
De
Revista:
Dtsch Med Wochenschr
Ano de publicação:
1995
Tipo de documento:
Article